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The novel metallo-β-lactamase PNGM-1 from a deep-sea sediment metagenome: crystallization and X-ray crystallographic analysis

Metallo-β-lactamases (MBLs) are present in major Gram-negative pathogens and environmental species, and pose great health risks because of their ability to hydrolyze the β-lactam rings of antibiotics such as carbapenems. PNGM-1 was the first reported case of a subclass B3 MBL protein that was identi...

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Bibliografski detalji
Izdano u:Acta Crystallogr F Struct Biol Commun
Glavni autori: Park, Kwang Seung, Hong, Myoung-Ki, Jeon, Jin Wan, Kim, Ji Hwan, Jeon, Jeong Ho, Lee, Jung Hun, Kim, Tae Yeong, Karim, Asad Mustafa, Malik, Sumera Kausar, Kang, Lin-Woo, Lee, Sang Hee
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168767/
https://ncbi.nlm.nih.gov/pubmed/30279316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18012268
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