Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

The presequence translocase of the mitochondrial inner membrane (TIM23 complex) facilitates anterograde precursor transport into the matrix and lateral release of precursors with stop-transfer signal into the membrane (sorting). Sorting requires precursor exit from the translocation channel into the...

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Publicado en:Nat Commun
Main Authors: Schendzielorz, Alexander Benjamin, Bragoszewski, Piotr, Naumenko, Nataliia, Gomkale, Ridhima, Schulz, Christian, Guiard, Bernard, Chacinska, Agnieszka, Rehling, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168564/
https://ncbi.nlm.nih.gov/pubmed/30279421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06492-8
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