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How phosphorylation influences E1 subunit pyruvate dehydrogenase: A computational study

Pyruvate (PYR) dehydrogenase complex (PDC) is an enzymatic system that plays a crucial role in cellular metabolism as it controls the entry of carbon into the Krebs cycle. From a structural point of view, PDC is formed by three different subunits (E1, E2 and E3) capable of catalyzing the three react...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Sgrignani, Jacopo, Chen, JingJing, Alimonti, Andrea, Cavalli, Andrea
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168537/
https://ncbi.nlm.nih.gov/pubmed/30279533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33048-z
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