Chemotherapy sensitizes therapy-resistant cells to mild hyperthermia by suppressing heat shock protein 27 expression in triple negative breast cancer

PURPOSE: Triple-negative breast cancer (TNBC) is a clinically aggressive disease with poor prognosis. Conventional chemotherapeutics are generally able to shrink the tumor mass, but often fail to completely eradicate cancer stem-like cells (CSCs) that are responsible for high risk of relapse and fre...

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Udgivet i:Clin Cancer Res
Main Authors: Mu, Chaofeng, Wu, Xiaoyan, Zhou, Xinyu, Wolfram, Joy, Shen, Jianliang, Zhang, Dechen, Mai, Junhua, Xia, Xiaojun, Holder, Ashley M., Ferrari, Mauro, Liu, Xuewu, Shen, Haifa
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168413/
https://ncbi.nlm.nih.gov/pubmed/29921732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3872
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