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Nanopore Label-free Detection of Single-nucleotide Deletion in Baxα/BaxΔ2

Baxα, a key tumor suppressor gene, will not be expressed correctly as a result of single nucleotide mutation in its microsatellite region; Instead, BaxΔ2, an isoform of Baxα, is often produced. In addition to lack of the exon 2 due to an alternative splicing, BaxΔ2 has the same sequence as Baxα exce...

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Detalhes bibliográficos
Publicado no:Electrophoresis
Main Authors: Chen, Xiaohan, Wang, Liang, Roozbahani, Golbarg M, Zhang, Youwen, Xiang, Jialing, Guan, Xiyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168411/
https://ncbi.nlm.nih.gov/pubmed/29998460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201800193
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