Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation

Cellular lipids determine membrane integrity and fluidity and are being increasingly recognized to influence immune responses. Cellular cholesterol requirements are fulfilled through biosynthesis and uptake programs. In an intricate pathway involving the lysosomal cholesterol transporter NPC1, the s...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: de la Roche, Marianne, Hamilton, Claire, Mortensen, Rebecca, Jeyaprakash, A. Arockia, Ghosh, Sanjay, Anand, Paras K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168277/
https://ncbi.nlm.nih.gov/pubmed/30054450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201709057
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