Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation

Spp1 is the H3K4me3 reader subunit of the Set1 complex (COMPASS/Set1C) that contributes to the mechanism by which meiotic DNA break sites are mechanistically selected. We previously proposed a model in which Spp1 interacts with H3K4me3 and the chromosome axis protein Mer2 that leads to DSB formation...

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Vydáno v:J Cell Biol
Hlavní autoři: Karányi, Zsolt, Halász, László, Acquaviva, Laurent, Jónás, Dávid, Hetey, Szabolcs, Boros-Oláh, Beáta, Peng, Feng, Chen, Doris, Klein, Franz, Géli, Vincent, Székvölgyi, Lóránt
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2018
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168271/
https://ncbi.nlm.nih.gov/pubmed/30037925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712122
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