Evaluation of CYP2D6 phenotype in the Yoruba Nigerian population

BACKGROUND: There is a lack of information on CYP2D6, a major metabolizing enzyme, in Africa ethnic nationalities. The objective was to determine CYP2D6 phenotype in Yoruba Nigerians using dextromethorphan (DEX). METHOD: A total of 89 healthy volunteers received 30 mg of DEX orally followed by blood...

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Vydáno v:Expert Rev Clin Pharmacol
Hlavní autoři: Adedeji, Waheed Adeola, Igbinoba, Sharon Iyobor, Fakeye, Titilayo O, Oladosu, Ibrahim Adebayo, Fehintola, Fatai Adewale, Ma, Qing, Morse, Gene D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168071/
https://ncbi.nlm.nih.gov/pubmed/28786716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17512433.2017.1362979
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