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What Can Diabetes-Associated Genetic Variation in TCF7L2 Teach Us About the Pathogenesis of Type 2 Diabetes?

Type 2 diabetes mellitus (T2DM) is a polygenic metabolic disorder characterized by hyperglycemia occurring as a result of impaired insulin secretion and/or insulin resistance. Among the various genetic factors associated with T2DM, a common genetic variant within the transcription factor 7-like 2 lo...

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Bibliografische gegevens
Gepubliceerd in:Metab Syndr Relat Disord
Hoofdauteurs: Adams, J.D., Vella, Adrian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc., publishers 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167616/
https://ncbi.nlm.nih.gov/pubmed/29993315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/met.2018.0024
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