Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer originating from mature B-cells. Prognosis is strongly associated with molecular subgroup, although the driver mutations that distinguish the two main subgroups remain poorly defined. Through an integrative analysis of whole genomes, exom...

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Publicat a:Nat Commun
Autors principals: Arthur, Sarah E., Jiang, Aixiang, Grande, Bruno M., Alcaide, Miguel, Cojocaru, Razvan, Rushton, Christopher K., Mottok, Anja, Hilton, Laura K., Lat, Prince Kumar, Zhao, Eric Y., Culibrk, Luka, Ennishi, Daisuke, Jessa, Selin, Chong, Lauren, Thomas, Nicole, Pararajalingam, Prasath, Meissner, Barbara, Boyle, Merrill, Davidson, Jordan, Bushell, Kevin R., Lai, Daniel, Farinha, Pedro, Slack, Graham W., Morin, Gregg B., Shah, Sohrab, Sen, Dipankar, Jones, Steven J. M., Mungall, Andrew J., Gascoyne, Randy D., Audas, Timothy E., Unrau, Peter, Marra, Marco A., Connors, Joseph M., Steidl, Christian, Scott, David W., Morin, Ryan D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167379/
https://ncbi.nlm.nih.gov/pubmed/30275490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06354-3
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