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MRI-guided intracerebral convection-enhanced injection of gliotoxins to induce focal demyelination in swine

Demyelinating disorders such as multiple sclerosis (MS) or transverse myelitis are devastating neurological conditions with no effective cure. Prevention of myelin loss or restoration of myelin are key for successful therapy. To investigate the disease and develop cures animal models with good clini...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kalkowski, Lukasz, Malysz-Cymborska, Izabela, Golubczyk, Dominika, Janowski, Miroslaw, Holak, Piotr, Milewska, Kamila, Kedziorek, Dorota, Adamiak, Zbigniew, Maksymowicz, Wojciech, Walczak, Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166947/
https://ncbi.nlm.nih.gov/pubmed/30273376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204650
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