Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds

Metastatic disease remains the primary cause of mortality in cancer patients. Yet the number of available in vitro models to study metastasis is limited by challenges in the recapitulation of the metastatic microenvironment in vitro, and by difficulties in maintaining colonized-tissue specificity in...

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Bibliographic Details
Published in:Nat Biomed Eng
Main Authors: Tian, Xi, Werner, Michael E., Roche, Kyle C., Hanson, Ariel D., Foote, Henry P., Yu, Stephanie K., Warner, Samuel B., Copp, Jonathan A., Lara, Haydee, Wauthier, Eliane L., Caster, Joseph M., Herring, Laura E., Zhang, Longzhen, Tepper, Joel E., Hsu, David S., Zhang, Tian, Reid, Lola M., Wang, Andrew Z.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166886/
https://ncbi.nlm.nih.gov/pubmed/31011191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0231-0
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