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Pentylenetetrazole (PTZ)-induced Convulsion Assay to DetermineGABAergic Defects in Caenorhabditis elegans

Pentylenetetrazole (PTZ) is a GABA(A) receptor antagonist and is used to monitor presynaptic defects in the release of the inhibitory neurotransmitter GABA. PTZ is a competitive inhibitor of GABA, and prevents binding of GABA on the GABA(A) receptors present on the surface of muscle. In the absence...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Thapliyal, Shruti, Babu, Kavita
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166856/
https://ncbi.nlm.nih.gov/pubmed/30283811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2989
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