Cerebrospinal fluid immunoglobulin light chain ratios predict disease progression in multiple sclerosis

OBJECTIVE: To determine whether the ratio of cerebrospinal fluid (CSF) immunoglobulin kappa to lambda light chains at time of multiple sclerosis (MS) diagnosis predicts disease progression and whether this was intrinsic to CSF plasmablasts. METHODS: CSF and peripheral blood were obtained from patien...

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Bibliografiske detaljer
Udgivet i:J Neurol Neurosurg Psychiatry
Main Authors: Rathbone, Emma, Durant, Lindsay, Kinsella, James, Parker, Antony R, Hassan-Smith, Ghaniah, Douglas, Michael R, Curnow, S John
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2018
Fag:
Multiple Sclerosis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166608/
https://ncbi.nlm.nih.gov/pubmed/29743290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2018-317947
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