Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis

BACKGROUND: Critically ill patients with impaired neutrophil phagocytosis have significantly increased risk of nosocomial infection. Granulocyte-macrophage colony-stimulating factor (GM-CSF) improves phagocytosis by neutrophils ex vivo. This study tested the hypothesis that GM-CSF improves neutrophi...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Pinder, Emma M, Rostron, Anthony J, Hellyer, Thomas P, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Macfarlane, James G, Wiscombe, Sarah, Widdrington, John D, Roy, Alistair I, Linnett, Vanessa C, Baudouin, Simon V, Wright, Stephen E, Chadwick, Thomas, Fouweather, Tony, Juss, Jatinder K, Chilvers, Edwin R, Bowett, Susan A, Parker, Jennie, McAuley, Daniel F, Conway Morris, Andrew, Simpson, A John
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166597/
https://ncbi.nlm.nih.gov/pubmed/30064991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2017-211323
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