Microfluidic generation of transient cell volume exchange for convectively driven intracellular delivery of large macromolecules

Efficient intracellular delivery of target macromolecules remains a major obstacle in cell engineering and other biomedical applications. We discovered a unique cell biophysical phenomenon of transient cell volume exchange by using microfluidics to rapidly and repeatedly compress cells. This behavio...

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Bibliographic Details
Published in:Mater Today (Kidlington)
Main Authors: Liu, Anna, Islam, Muhymin, Stone, Nicholas, Varadarajan, Vikram, Jeong, Jenny, Bowie, Sam, Qiu, Peng, Waller, Edmund K., Alexeev, Alexander, Sulchek, Todd
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166476/
https://ncbi.nlm.nih.gov/pubmed/30288138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mattod.2018.03.002
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