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Purinergic Vasotoxicity: Role of the Pore/Oxidant/K(ATP) Channel/Ca(2+) Pathway in P2X(7)-Induced Cell Death in Retinal Capillaries

P2X(7) receptor/channels in the retinal microvasculature not only regulate vasomotor activity, but can also trigger cells in the capillaries to die. While it is known that this purinergic vasotoxicity is dependent on the transmembrane pores that form during P2X(7) activation, events linking pore for...

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Detalhes bibliográficos
Publicado no:Vision (Basel)
Main Authors: Shibata, Maho, Ishizaki, Eisuke, Zhang, Ting, Fukumoto, Masanori, Barajas-Espinosa, Alma, Li, Tong, Puro, Donald G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166475/
https://ncbi.nlm.nih.gov/pubmed/30288454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vision2030025
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