Maternal obesity has sex‐dependent effects on insulin, glucose and lipid metabolism and the liver transcriptome in young adult rat offspring

KEY POINTS: Maternal high‐fat diet consumption predisposes to metabolic dysfunction in male and female offspring at young adulthood. Maternal obesity programs non‐alcoholic fatty liver disease (NAFLD) in a sex‐dependent manner. We demonstrate sex‐dependent liver transcriptome profiles in rat offspri...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Lomas‐Soria, Consuelo, Reyes‐Castro, Luis A., Rodríguez‐González, Guadalupe L., Ibáñez, Carlos A., Bautista, Claudia J., Cox, Laura A., Nathanielsz, Peter W., Zambrano, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Molecular and cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166072/
https://ncbi.nlm.nih.gov/pubmed/29972240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276372
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