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Adaptive Steered Molecular Dynamics Combined With Protein Structure Networks Revealing the Mechanism of Y68I/G109P Mutations That Enhance the Catalytic Activity of D-psicose 3-Epimerase From Clostridium Bolteae

The scarcity, richness, and other important physiological functions of D-psicose make it crucial to increase the yield of D-psicose. The production of D-psicose can be accomplished by D-psicose 3-epimerase (DPEase) from Clostridium bolteae (CbDPEase) catalyzing the substrate D-fructose. Although the...

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Publicat a:Front Chem
Autors principals: Zhu, Jingxuan, Li, Yi, Wang, Jinzhi, Yu, Zhengfei, Liu, Ye, Tong, Yi, Han, Weiwei
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166005/
https://ncbi.nlm.nih.gov/pubmed/30320068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00437
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