Inhibition of Prostate Cancer DU-145 Cells Proliferation by Anthopleura anjunae Oligopeptide (YVPGP) via PI3K/AKT/mTOR Signaling Pathway

We investigated the antitumor mechanism of Anthopleura anjunae oligopeptide (AAP-H, YVPGP) in prostate cancer DU-145 cells in vitro and in vivo. Results indicated that AAP-H was nontoxic and exhibited antitumor activities. Cell cycle analysis indicated that AAP-H may arrest DU-145 cells in the S pha...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Li, Xiaojuan, Tang, Yunping, Yu, Fangmiao, Sun, Yu, Huang, Fangfang, Chen, Yan, Yang, Zuisu, Ding, Guofang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165336/
https://ncbi.nlm.nih.gov/pubmed/30208576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16090325
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