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Radiation Sensitization of Basal Cell and Head and Neck Squamous Cell Carcinoma by the Hedgehog Pathway Inhibitor Vismodegib

Vismodegib, an inhibitor of the Hedgehog signaling pathway, is an approved drug for monotherapy in locally advanced or metastatic basal cell carcinoma (BCC). Data on combined modality treatment by vismodegib and radiation therapy, however, are rare. In the present study, we examined the radiation se...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hehlgans, Stephanie, Booms, Patrick, Güllülü, Ömer, Sader, Robert, Rödel, Claus, Balermpas, Panagiotis, Rödel, Franz, Ghanaati, Shahram
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164565/
https://ncbi.nlm.nih.gov/pubmed/30142876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092485
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