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In Silico HCT116 Human Colon Cancer Cell-Based Models En Route to the Discovery of Lead-Like Anticancer Drugs

To discover new inhibitors against the human colon carcinoma HCT116 cell line, two quantitative structure–activity relationship (QSAR) studies using molecular and nuclear magnetic resonance (NMR) descriptors were developed through exploration of machine learning techniques and using the value of hal...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Cruz, Sara, Gomes, Sofia E., Borralho, Pedro M., Rodrigues, Cecília M. P., Gaudêncio, Susana P., Pereira, Florbela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164384/
https://ncbi.nlm.nih.gov/pubmed/30018273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8030056
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