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Thyroxin Protects White Matter from Hypoxic-Ischemic Insult in the Immature Sprague–Dawley Rat Brain by Regulating Periventricular White Matter and Cortex BDNF and CREB Pathways

Background: Periventricular white-matter (WM) injury is a prominent feature of brain injury in preterm infants. Thyroxin (T4) treatment reduces the severity of hypoxic-ischemic (HI)-mediated WM injury in the immature brain. This study aimed to delineate molecular events underlying T4 protection foll...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hung, Pi-Lien, Hsu, Mei-Hsin, Yu, Hong-Ren, Wu, Kay L. H., Wang, Feng-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164053/
https://ncbi.nlm.nih.gov/pubmed/30158497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092573
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