Expression of the OAS Gene Family Is Highly Modulated in Subjects Affected by Juvenile Dermatomyositis, Resembling an Immune Response to a dsRNA Virus Infection

Background: Juvenile dermatomyositis (JDM) is a systemic, autoimmune, interferon (IFN)-mediated inflammatory muscle disorder that affects children younger than 18 years of age. JDM primarily affects the skin and the skeletal muscles. Interestingly, the role of viral infections has been hypothesized....

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Musumeci, Giuseppe, Castrogiovanni, Paola, Barbagallo, Ignazio, Tibullo, Daniele, Sanfilippo, Cristina, Nunnari, Giuseppe, Pellicanò, Giovanni Francesco, Pavone, Piero, Caltabiano, Rosario, Di Marco, Roberto, Imbesi, Rosa, Di Rosa, Michelino
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163680/
https://ncbi.nlm.nih.gov/pubmed/30227596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092786
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