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Inflammatory mediators reduce surface PrP(c) on human BMVEC resulting in decreased barrier integrity
The cellular prion protein (PrP(c)) is a surface adhesion molecule expressed at junctions of various cell types including brain microvascular endothelial cells (BMVEC) that are important components of the blood brain barrier (BBB). PrP(c) is involved in several physiological processes including regu...
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| Veröffentlicht in: | Lab Invest |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6163073/ https://ncbi.nlm.nih.gov/pubmed/29959417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0090-z |
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