All-trans retinoic acid-encapsulated, CD20 antibody-conjugated poly(lactic-co-glycolic acid) nanoparticles effectively target and eliminate melanoma-initiating cells in vitro

PURPOSE: Melanoma, which is initiated from melanocytes, is the most fatal type of skin cancer. Melanoma-initiating cells significantly contribute to the initiation, metastasis, and recurrence of melanoma, and CD20 is a marker of melanoma-initiating cells. All-trans retinoic acid (ATRA) has been demo...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Chen, Xingyu, Zhang, Zhiyuan, Yang, Shengfeng, Chen, Hairong, Wang, Dan, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163018/
https://ncbi.nlm.nih.gov/pubmed/30288053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S169957
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