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SOX2, a stemness gene, induces progression of NSCLC A549 cells toward anchorage-independent growth and chemoresistance to vinblastine

BACKGROUND: Non-small cell lung cancer (NSCLC) is difficult to treat successfully. This intractability is mainly due to the cancer progressing through invasion, metastasis, chemotherapeutic resistance and relapse. Stemness has been linked to the various steps of cancer progression in a variety of tu...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Choe, Chungyoul, Kim, Hyewon, Min, Sol, Park, Sangkyu, Seo, Jeongmin, Roh, Sangho
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163012/
https://ncbi.nlm.nih.gov/pubmed/30288055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S175810
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