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From association to mechanism in complex disease genetics: the role of the 3D genome
Genome-wide association studies (GWAS) and fine mapping studies in autoimmune diseases have identified thousands of genetic variants, the majority of which are located in non-protein-coding enhancer regions. Enhancers function within the context of the three-dimensional (3D) genome to form long-rang...
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| Pubblicato in: | Arthritis Res Ther |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6162955/ https://ncbi.nlm.nih.gov/pubmed/30268153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1721-x |
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