Potential Impact of COMT-rs4680 G > A Gene Polymorphism in Coronary Artery Disease

Purpose: Catechol-O-methyltransferase (COMT) plays a central role in DNA repair and estrogen-induced carcinogenesis. The nonsynonymous single nucleotide polymorphism (SNP) in exon 4 G > A or Val108 > 158Met or rs4680 G > A influences COMT enzyme activity. The three phenotypes of the COMT en...

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Udgivet i:J Cardiovasc Dev Dis
Main Authors: Mir, Rashid, Bhat, Musadiq, Javid, Jamsheed, Jha, Chandan, Saxena, Alpana, Banu, Shaheen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162781/
https://ncbi.nlm.nih.gov/pubmed/30011860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcdd5030038
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