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The Dual Immunoregulatory function of Nlrp12 in T Cell-Mediated Immune Response: Lessons from Experimental Autoimmune Encephalomyelitis

Although the etiology of multiple sclerosis (MS) remains enigmatic, the role of T cells is unquestionably central in this pathology. Immune cells respond to pathogens and danger signals via pattern-recognition receptors (PRR). Several reports implicate Nlrp12, an intracellular PRR, in the developmen...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Gharagozloo, Marjan, Mahmoud, Shaimaa, Simard, Camille, Mahvelati, Tara M., Amrani, Abdelaziz, Gris, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162721/
https://ncbi.nlm.nih.gov/pubmed/30150571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7090119
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