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Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions
Focal adhesion kinase (FAK) is a cytoplasmic non-receptor protein tyrosine kinase that is overexpressed and activated in many human cancers. FAK transmits signals to a wide range of targets through both kinase-dependant and independent mechanism thereby playing essential roles in cell survival, prol...
Guardat en:
| Publicat a: | Cancers (Basel) |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6162372/ https://ncbi.nlm.nih.gov/pubmed/30134553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10090278 |
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