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An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
Cyclic nucleotide-gated (CNG) ion channels are non-selective cation channels key to signal transduction. The free energy difference of cyclic-nucleotide (cAMP/cGMP) binding/unbinding is translated into mechanical work to modulate the open/closed probability of the pore, i.e., gating. Despite the rec...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6162275/ https://ncbi.nlm.nih.gov/pubmed/30266906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06414-8 |
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