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Kappa opioid regulation of depressive-like behavior during acute withdrawal and protracted abstinence from ethanol

The dynorphin/kappa opioid receptor (DYN/KOR) system appears to be a key mediator of the behavioral effects of chronic exposure to alcohol. Although KOR opioid receptor antagonists have been shown to decrease stress-related behaviors in animal models during acute ethanol withdrawal, the role of the...

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發表在:PLoS One
Main Authors: Jarman, Sorscha K., Haney, Alison M., Valdez, Glenn R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161915/
https://ncbi.nlm.nih.gov/pubmed/30265734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205016
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