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Intratumor heterogeneity of HMCN1 mutant alleles associated with poor prognosis in patients with breast cancer

Human breast cancers comprise a complex and highly heterogeneous population of tumor cells. Intratumor heterogeneity is an underlying cause of resistance to effective therapies and disease recurrence. To explore prognostic factors based on intratumor heterogeneity, we analyzed genomic mutations in b...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kikutake, Chie, Yoshihara, Minako, Sato, Tetsuya, Saito, Daisuke, Suyama, Mikita
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161790/
https://ncbi.nlm.nih.gov/pubmed/30279964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26071
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