The C-terminal p6 domain of the HIV-1 Pr55(Gag) precursor is required for specific binding to the genomic RNA

The Pr55(Gag) precursor specifically selects the HIV-1 genomic RNA (gRNA) from a large excess of cellular and partially or fully spliced viral RNAs and drives the virus assembly at the plasma membrane. During these processes, the NC domain of Pr55(Gag) interacts with the gRNA, while its C-terminal p...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Dubois, Noé, Khoo, Keith K., Ghossein, Shannon, Seissler, Tanja, Wolff, Philippe, McKinstry, William J., Mak, Johnson, Paillart, Jean-Christophe, Marquet, Roland, Bernacchi, Serena
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161697/
https://ncbi.nlm.nih.gov/pubmed/29954247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1481696
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