Antiepileptic drug clearances during pregnancy and clinical implications for women with epilepsy

OBJECTIVE: To characterize the magnitude and time course of pregnancy-related clearance changes for different antiepileptic drugs (AEDs): levetiracetam, oxcarbazepine, topiramate, phenytoin, and valproate. A secondary aim was to determine if a decreased AED serum concentration was associated with in...

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Bibliografske podrobnosti
izdano v:Neurology
Main Authors: Voinescu, P. Emanuela, Park, Suna, Chen, Li Q., Stowe, Zachary N., Newport, D. Jeffrey, Ritchie, James C., Pennell, Page B.
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161546/
https://ncbi.nlm.nih.gov/pubmed/30185446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000006240
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