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Pharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine

A sensitive and simple chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to evaluate memantine in rat plasma. Memantine and propranolol (internal standard) in rat plasma was extracted using a methanol precipitation method. The standard curve value was 0.2–1000 ng/mL and selecti...

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Vydáno v:Pharmaceutics
Hlavní autoři: Choi, Young A., Song, Im-Sook, Choi, Min-Koo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161283/
https://ncbi.nlm.nih.gov/pubmed/30082658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030119
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