Development and Evaluation of a Reconstitutable Dry Suspension to Improve the Dissolution and Oral Absorption of Poorly Water-Soluble Celecoxib

This study aims at developing and evaluating reconstitutable dry suspension (RDS) improved for dissolution rate, oral absorption, and convenience of use of poorly water-soluble celecoxib (CXB). Micro-sized CXB particle was used to manufacture nanosuspension by using bead milling and then RDS was mad...

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Veröffentlicht in:Pharmaceutics
Hauptverfasser: Kim, Hye-In, Park, Sang Yeob, Park, Seok Ju, Lee, Jewon, Cho, Kwan Hyung, Jee, Jun-Pil, Kim, Hee-Cheol, Maeng, Han-Joo, Jang, Dong-Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161273/
https://ncbi.nlm.nih.gov/pubmed/30158472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030140
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