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Intrauterine Exposure to Cadmium Reduces HIF-1 DNA-Binding Ability in Rat Fetal Kidneys

During embryonic development, some hypoxia occurs due to incipient vascularization. Under hypoxic conditions, gene expression is mainly controlled by hypoxia-inducible factor 1 (HIF-1). The activity of this transcription factor can be altered by the exposure to a variety of compounds; among them is...

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Библиографические подробности
Опубликовано в: :Toxics
Главные авторы: Jacobo-Estrada, Tania, Cardenas-Gonzalez, Mariana, Santoyo-Sánchez, Mitzi Paola, Thevenod, Frank, Barbier, Olivier
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161213/
https://ncbi.nlm.nih.gov/pubmed/30177602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxics6030053
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