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Validation of Model-Based Melt Viscosity in Hot-Melt Extrusion Numerical Simulation

A validation for the use of model-based melt viscosity in hot-melt extrusion numerical simulations was presented. Here, the melt viscosity of an amorphous solid dispersion (ASD) was calculated by using its glass transition temperature (T(g)) and the rheological flow profile of the pure polymeric mat...

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Foilsithe in:Pharmaceutics
Main Authors: Bochmann, Esther S., Gryczke, Andreas, Wagner, Karl G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161212/
https://ncbi.nlm.nih.gov/pubmed/30126193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030132
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