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Neutralizing Anti-Hemagglutinin Monoclonal Antibodies Induced by Gene-Based Transfer Have Prophylactic and Therapeutic Effects on Influenza Virus Infection

Hemagglutinin (HA) of influenza virus is a major target for vaccines. HA initiates the internalization of the virus into the host cell by binding to host sialic acid receptors; therefore, inhibition of HA can significantly prevent influenza virus infection. However, the high diversity of HA permits...

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Библиографические подробности
Опубликовано в: :Vaccines (Basel)
Главные авторы: Yamazaki, Tatsuya, Chiba, Joe, Akashi-Takamura, Sachiko
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161145/
https://ncbi.nlm.nih.gov/pubmed/29949942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines6030035
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