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Raloxifene/SBE-β-CD Inclusion Complexes Formulated into Nanoparticles with Chitosan to Overcome the Absorption Barrier for Bioavailability Enhancement

Raloxifene (RXF) is a hormone-like medication used for treating postmenopausal osteoporosis and estrogen-dependent breast cancer, yet associated with bad low bioavailability due to poor solubility. This study was intended to develop cyclodextrin/chitosan nanoparticles (ccNPs) for oral delivery of RX...

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Detalles Bibliográficos
Publicado en:Pharmaceutics
Main Authors: Wang, Zaihua, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160996/
https://ncbi.nlm.nih.gov/pubmed/29958389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030076
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