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Dipeptidyl peptidase-4 inhibitors have adverse effects for the proliferation of human T cells

Dipeptidyl peptidase-4 (DPP-4) is a critical molecule for the metabolism of incretins. In addition, DPP-4 is known as CD26, the receptor of T cells, and plays important role in activation of T cells. Recently, DPP-4 inhibitors (DPP4i) are reported to have several immunologic effects beyond glycemic...

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Bibliographic Details
Published in:J Clin Biochem Nutr
Main Authors: Kitagawa, Noriyuki, Hamaguchi, Masahide, Majima, Saori, Fukuda, Takuya, Kimura, Toshihiro, Hashimoto, Yoshitaka, Tanaka, Muhei, Yamazaki, Masahiro, Nakamura, Naoto, Fukui, Michiaki
Format: Artigo
Language:Inglês
Published: the Society for Free Radical Research Japan 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160731/
https://ncbi.nlm.nih.gov/pubmed/30279621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.17-64
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