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Clopidogrel as a donor probe and thioenol derivatives as flexible promoieties for enabling H(2)S biomedicine

Hydrogen sulfide has emerged as a critical endogenous signaling transmitter and a potentially versatile therapeutic agent. The key challenges in this field include the lack of approved hydrogen sulfide-releasing probes for in human exploration and the lack of controllable hydrogen sulfide promoietie...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhu, Yaoqiu, Romero, Elkin L., Ren, Xiaodong, Sanca, Angel J., Du, Congkuo, Liu, Cai, Karim, Zubair A., Alshbool, Fatima Z., Khasawneh, Fadi T., Zhou, Jiang, Zhong, Dafang, Geng, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160475/
https://ncbi.nlm.nih.gov/pubmed/30262863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06373-0
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