Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancer

PD-L1, a key inhibitory immune receptor, has crucial functions in cancer immune evasion, but whether PD-L1 promotes the malignant properties of cervical cancer (CC) cells and the mechanism by which PD-L1 is regulated in CC remains unclear. We report that PD-L1 is overexpressed in CC, and shRNA-media...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Dong, Peixin, Xiong, Ying, Yu, Jiehai, Chen, Lin, Tao, Tang, Yi, Song, Hanley, Sharon J. B., Yue, Junming, Watari, Hidemichi, Sakuragi, Noriaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160397/
https://ncbi.nlm.nih.gov/pubmed/29855617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0347-4
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