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Role of brain-derived neurotrophic factor in the pathogenesis of distention-associated abdominal pain in bowel obstruction

BACKGROUND: Previous studies found that visceral sensitivity is increased in bowel obstruction (BO). We hypothesized that mechanical stress-induced expression of BDNF in smooth muscle cells (SMC) of the distended bowel plays a critical role in visceral hypersensitivity in BO by altering voltage-gate...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurogastroenterol Motil
Prif Awduron: Fu, Yu, Lin, You-Min, Winston, John H., Radhakrishnan, Ravi, Huang, Li-Yen M., Shi, Xuan-Zheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160336/
https://ncbi.nlm.nih.gov/pubmed/29781158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.13373
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