Comparative study of esketamine and racemic ketamine in treatment-resistant depression: Protocol for a non-inferiority clinical trial

INTRODUCTION: The use of ketamine as an option in the treatment of depressive disorder is growing rapidly, supported by numerous clinical trials attesting its efficacy and safety. Esketamine, the S (+) enantiomer of ketamine, is the most widely used form in the anesthetic environment in some countri...

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Publicat a:Medicine (Baltimore)
Autors principals: Correia-Melo, Fernanda S., Leal, Gustavo C., Carvalho, Michelle S., Jesus-Nunes, Ana Paula, Ferreira, Carolina B.N., Vieira, Flávia, Magnavita, Guilherme, Vale, Lucas A.S., Mello, Rodrigo P., Nakahira, Carolina, Argolo, Felipe C., Cardoso, Tanise, Souza, Cezar D.S., Fontes, Ana Teresa C., Ferreira, Marcelo B., Araújo-de-Freitas, Lucas, Tuena, Marco A., Echegaray, Mariana V.F., Cavalcanti, Diogo E., Lucchese, Ana C., Bandeira, Igor D., Telles, Manuela, Lima, Cássio S., Sampaio, Aline S., Silva, Samantha S., Marback, Roberta F., Del-Porto, José A., Abreu, José Neander, Sarin, Luciana M., Paixão, Camilla S., Carvalho, Lucas P., Machado, Paulo R.L., Turecki, Gustavo, Lacerda, Acioly L.T., Quarantini, Lucas C.
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160185/
https://ncbi.nlm.nih.gov/pubmed/30235716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000012414
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