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Oxidative stress and the altered reaction to it in Fabry disease: A possible target for cardiovascular-renal remodeling?
BACKGROUND: Fabry disease is characterized by deficient expression/activity of α-GalA with consequent lysosomal accumulation in various organs of its substrate Gb3. Despite enzyme replacement therapy, Fabry disease progresses with serious myocardial, cerebral and renal manifestations. Gb3 accumulati...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6160124/ https://ncbi.nlm.nih.gov/pubmed/30261035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204618 |
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