rs4246215 is targeted by hsa-miR1236 to regulate FEN1 expression but is not associated with Fuchs’ endothelial corneal dystrophy

Fuchs’ Endothelial Corneal Dystrophy (FECD) is a genetically complex disorder that affects individuals above 40 years of age; molecular pathogenesis of its associated genes is poorly understood. This study aims at assessing the association of flap endonuclease 1 (FEN1) polymorphisms, c.-69G>A (rs...

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Опубликовано в: :PLoS One
Главные авторы: Nanda, Gargi Gouranga, Kumar, Malloji Vinay, Pradhan, Laxmipriya, Padhy, Biswajit, Sundaray, Satabdi, Das, Sujata, Alone, Debasmita Pankaj
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160067/
https://ncbi.nlm.nih.gov/pubmed/30260965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204278
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