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GPx3-mediated redox signaling arrests the cell cycle and acts as a tumor suppressor in lung cancer cell lines

Glutathione peroxidase 3 (GPx3), a major scavenger of reactive oxygen species (ROS) in plasma, acts as a redox signal modulator. However, the mechanism underlying GPx3-mediated suppression of cancer cell growth is unclear. The aim of this study was to identify these mechanisms with respect to lung c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: An, Byung Chull, Choi, Yoo-Duk, Oh, In-Jae, Kim, Ju Han, Park, Jae-Il, Lee, Seung-won
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160013/
https://ncbi.nlm.nih.gov/pubmed/30260967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204170
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